Journal Reviews

Transcriptomic analysis of ocular tissues

1 August 2018 | | Glaucoma | Ciliary body, Cornea, Gene expression, Glaucoma, RNA sequencing, Trabecular meshwork, Transcriptome

Transcriptomics is defined as the analysis of the complete set of RNA transcripts present in a cell under different circumstances, quiescent versus challenge, by microarray analysis. Comparison of transcriptomes identifies genes that are differentially expressed in different cell populations under...

Resveratrol protects against steroid induced intraocular pressure

1 April 2016 | | Genetics | Glaucoma, Intraocular pressure, Resveratrol, Retina, Steroid-induced, Trabecular meshwork

Topical and systemic steroid delivery is a very effective treatment for many ocular conditions but is compromised by raised intraocular pressure which in turn leads to death of retinal ganglion cells and irreversible blindness. This is an important consideration with...